Treatment Comparison 45E1B0
1. **Problem Statement:** Determine whether the new treatment is comparatively superior to the conventional treatment based on the given data:
| Treatment | Favourable | Non Favourable |
|--------------|------------|---------------|
| New | 60 | 30 |
| Conventional | 40 | 70 |
2. **Method:** Use the Chi-square test for independence to check if the treatment type and outcome are related.
3. **Formula:**
$$\chi^2 = \sum \frac{(O - E)^2}{E}$$
where $O$ is observed frequency and $E$ is expected frequency.
4. **Calculate totals:**
- Total patients = $60 + 30 + 40 + 70 = 200$
- Total favourable = $60 + 40 = 100$
- Total non favourable = $30 + 70 = 100$
- Total new treatment = $60 + 30 = 90$
- Total conventional = $40 + 70 = 110$
5. **Calculate expected frequencies:**
- $E_{New,Favourable} = \frac{90 \times 100}{200} = 45$
- $E_{New,NonFavourable} = \frac{90 \times 100}{200} = 45$
- $E_{Conv,Favourable} = \frac{110 \times 100}{200} = 55$
- $E_{Conv,NonFavourable} = \frac{110 \times 100}{200} = 55$
6. **Calculate Chi-square statistic:**
$$\chi^2 = \frac{(60-45)^2}{45} + \frac{(30-45)^2}{45} + \frac{(40-55)^2}{55} + \frac{(70-55)^2}{55}$$
$$= \frac{15^2}{45} + \frac{(-15)^2}{45} + \frac{(-15)^2}{55} + \frac{15^2}{55}$$
$$= \frac{225}{45} + \frac{225}{45} + \frac{225}{55} + \frac{225}{55}$$
$$= 5 + 5 + 4.09 + 4.09 = 18.18$$
7. **Degrees of freedom:**
$df = (rows - 1)(columns - 1) = (2-1)(2-1) = 1$
8. **Decision:**
At $df=1$, the critical value of $\chi^2$ at 5% significance is 3.841.
Since $18.18 > 3.841$, we reject the null hypothesis.
9. **Conclusion:**
There is a significant association between treatment type and outcome. The new treatment is comparatively superior to the conventional treatment because it has more favourable outcomes.
**Final answer:** The new treatment is statistically superior to the conventional treatment based on the Chi-square test.