Test Positive Probability 18Abcf
1. **Problem statement:**
A patient undergoes two independent diagnostic tests for the same disease. Each test has 90% sensitivity and 95% specificity.
We want to find:
a) The probability that both tests return positive for a person who has the disease.
b) The probability that both tests return positive for a person who does not have the disease.
2. **Definitions and formulas:**
- Sensitivity is the probability that the test is positive given the person has the disease: $P(\text{Test}^+|\text{Disease}) = 0.9$.
- Specificity is the probability that the test is negative given the person does not have the disease: $P(\text{Test}^-|\text{No Disease}) = 0.95$.
Since the tests are independent, the joint probability of both tests being positive is the product of their individual probabilities.
3. **Calculations:**
**a) Both tests positive given disease:**
$$
P(\text{Both}^+|\text{Disease}) = P(\text{Test}_1^+|\text{Disease}) \times P(\text{Test}_2^+|\text{Disease}) = 0.9 \times 0.9 = 0.81
$$
**b) Both tests positive given no disease:**
First, find the probability that a test is positive given no disease:
$$
P(\text{Test}^+|\text{No Disease}) = 1 - P(\text{Test}^-|\text{No Disease}) = 1 - 0.95 = 0.05
$$
Then,
$$
P(\text{Both}^+|\text{No Disease}) = 0.05 \times 0.05 = 0.0025
$$
4. **Interpretation:**
- For a person with the disease, there is an 81% chance both tests will be positive.
- For a person without the disease, there is a 0.25% chance both tests will be falsely positive.
**Final answers:**
- a) $0.81$
- b) $0.0025$