1. The problem states that point E has an x-coordinate that is not 0 and a y-coordinate that is negative. 2. Recall the signs of coordinates in each quadrant: - Quadrant I: $x > 0$, $y > 0$ - Quadrant II: $x < 0$, $y > 0$ - Quadrant III: $x < 0$, $y < 0$ - Quadrant IV: $x > 0$, $y < 0$ 3. Since the y-coordinate of point E is negative, point E must be in either Quadrant III or Quadrant IV. 4. Since the x-coordinate is not zero, point E cannot lie on the y-axis. 5. Therefore, point E is located in either Quadrant III (if $x < 0$) or Quadrant IV (if $x > 0$). Final answer: Point E is in Quadrant III or Quadrant IV.