1. The problem shows a sequence of operations starting with the number 4. 2. First, we add 3 to 4. Using the formula for addition: $$4 + 3 = 7$$. 3. The result after the first operation is 7, so the first empty box should contain 7. 4. Next, we subtract 10 from the result 7. Using the formula for subtraction: $$7 - 10 = -3$$. 5. The final empty box should contain the number $$-3$$. 6. Therefore, the number that goes in the final box is $$-3$$.