1. The problem asks to fill in the blanks for multiplication and division with positive and negative numbers. 2. a) Calculate $4 \times (-6)$. $$4 \times (-6) = -24$$ Answer: -24 3. b) Calculate $(-4) \times (-6)$. $$(-4) \times (-6) = 24$$ Answer: 24 4. c) Calculate $(-24) \div 6$. $$(-24) \div 6 = -4$$ Answer: -4 5. d) Calculate $(-4) \times 6$. $$(-4) \times 6 = -24$$ Answer: -24 6. e) Calculate $24 \div (-6)$. $$24 \div (-6) = -4$$ Answer: -4 7. f) Calculate $(-24) \div (-6)$. $$(-24) \div (-6) = 4$$ Answer: 4 Each operation uses the rules: multiplication/division of one positive and one negative number is negative, and two negatives make a positive.